The prosecution said that if the UN's Yugoslav war crimes court required it to limit the scope of the case against Karadzic it could restrict testimony to evidence related to only certain municipalities, crime sites and incidents related to the Srebrenica enclave and Sarajevo siege.
"Any further reduction may result in an indictment that is no longer reasonably representative of the case as a whole and would negatively affect the prosecution’s ability to fairly present its case," the document said.
Karadzic is due to stand trial at the International Criminal Tribunal for the former Yugoslavia (ICTY), possibly from this month, for his part in the 1992-95 war in the former Yugoslav republic of Bosnia.
He faces 11 charges related mainly to his role in the 44-month siege of Sarajevo, which left 10,000 people dead, and the July 1995 massacre of around 8,000 Muslim men and boys at Srebrenica.
He had been on the run for 13 years before his arrest last year on a suburban bus disguised as a heavily-bearded alternative medicine healer.
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