Two of the Belgian jets were flying their first reconnaissance missions over Iraqi territory on Sunday when they were called to action.
"After the positive identification of a terrorist element attacking Iraqi security forces", one of the war planes was asked to launch an air strike, the ministry said in a statement.
"The Belgian aircraft intervened with a GPS-guided bomb, resulting in the immediate neutralisation of the enemy threat," it added.
Belgium's parliament overwhelmingly approved joining the US-led coalition against IS in late September, but limited its operations to Iraq -- as have France, Britain, Denmark and the Netherlands.
The United States and several Arab coalition partners have been conducting air strikes against IS in Syria.
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"After the positive identification of a terrorist element attacking Iraqi security forces", one of the war planes was asked to launch an air strike, the ministry said in a statement.
"The Belgian aircraft intervened with a GPS-guided bomb, resulting in the immediate neutralisation of the enemy threat," it added.
Belgium's parliament overwhelmingly approved joining the US-led coalition against IS in late September, but limited its operations to Iraq -- as have France, Britain, Denmark and the Netherlands.
The United States and several Arab coalition partners have been conducting air strikes against IS in Syria.
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