The record appearance holder for Leeds was diagnosed with lymphoma and suffered from dementia.
Leeds confirmed the sad news on Saturday morning with a statement that said: "Charlton's contribution to the game and Leeds United will never be forgotten.
"He will remain in football folklore forever and his records at Leeds United are unlikely ever to be surpassed."
Charlton was a one-club man for his entire playing career after joining Leeds aged 15 in 1950 before going on to make a record 773 appearances.
He helped the club get promoted to the First Division twice before winning the top flight in 1968-69 as well as an FA Cup in 1971.
Internationally, he earned his first England call-up in 1965 and a year later, Charlton featured in every game of England's 1966 World Cup success, where they beat West Germany 4-2 in the final. He had a total of 35 England caps.
After his retirement in 1973, Charlton became a successful manager by leading the Republic of Ireland to their first major finals at Euro 1988 and the World Cup quarter-finals two years later in Italy.
Leeds confirmed the sad news on Saturday morning with a statement that said: "Charlton's contribution to the game and Leeds United will never be forgotten.
"He will remain in football folklore forever and his records at Leeds United are unlikely ever to be surpassed."
Charlton was a one-club man for his entire playing career after joining Leeds aged 15 in 1950 before going on to make a record 773 appearances.
He helped the club get promoted to the First Division twice before winning the top flight in 1968-69 as well as an FA Cup in 1971.
Internationally, he earned his first England call-up in 1965 and a year later, Charlton featured in every game of England's 1966 World Cup success, where they beat West Germany 4-2 in the final. He had a total of 35 England caps.
After his retirement in 1973, Charlton became a successful manager by leading the Republic of Ireland to their first major finals at Euro 1988 and the World Cup quarter-finals two years later in Italy.