"The thwarted attack included plans to launch a number of armed drones intended to be used to strike Israeli sites," it added.
Army spokesman Jonathan Conricus said the army struck infrastructure with fighter jets and explained that a "killer drone" can be equipped with explosives and is like a missile "capable of striking targets with significant accuracy."
Prime Minister and Defence Minister Benjamin Netanyahu said in a statement: "I reiterate: Iran has no immunity anywhere. Our forces operate in every sector against the Iranian aggression."
"I have directed that our forces be prepared for any scenario," he added. "We will continue to take determined and responsible action against Iran and its proxies for the security of Israel."
Amid the civil war in neighbouring Syria, Israel has repeatedly launched airstrikes against Iranian targets in Syria, stressing that it will not allow Iran to entrench itself militarily in the country.
Syria and Israel have never signed a peace deal, and the countries remain staunch regional rivals.
It is rare for Israel to comment on its strikes in Syria.
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