Russia is "very concerned" by the strikes that "directly targeted the Syrian army, which has been consistently fighting the Islamic State group's forces", she added.
The bombing hit an army position in the east, near the IS-controlled town of Deir Ezzor, a Russian army statement said.
At least 62 soldiers were killed in the strike, according to Russian officials and a Syrian monitoring group.
"These strikes endanger everything that has been done so far by the international community" to reach peace in Syria, the Russian foreign ministry spokeswoman said.
Zakharova accused the United States of being "simply incapable of honoring its commitment" to distinguish between jihadists and Syrian mainstream rebels in the implementation of a ceasefire in force since Monday.
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The bombing hit an army position in the east, near the IS-controlled town of Deir Ezzor, a Russian army statement said.
At least 62 soldiers were killed in the strike, according to Russian officials and a Syrian monitoring group.
"These strikes endanger everything that has been done so far by the international community" to reach peace in Syria, the Russian foreign ministry spokeswoman said.
Zakharova accused the United States of being "simply incapable of honoring its commitment" to distinguish between jihadists and Syrian mainstream rebels in the implementation of a ceasefire in force since Monday.
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